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Together, let’s sound the alarm against cancer


There’s a vibrant, loud energy at Siren. That kind of excited, expectant energy you only feel when you’re about to try something new.

When you jump in feet first, eyes wide open. When you visualize the endless opportunities ahead. When you run toward a challenge, knowing that the higher the stakes, the sweeter the reward.

That energy. It's here.

At Siren, everyone contributes and collaborates. Everyone works hard. Everyone is an innovator. Everyone is supportive. Everyone is passionate. Everyone is dedicated. Everyone is an owner.

Everyone wants to make a difference for cancer patients. A BIG difference.

We’re growing our team, and we’d love to meet you!

View Open Opportunities

Fast Facts

Siren Biotechnology

Award-Winning Academic Spinout

University of California San Francisco (UCSF) academic spin-out from the Paulk Lab

Woman-Founded and Led

Nicole Paulk, Ph.D. Founder, CEO & President, Global AAV Leader

Located in Mission Bay

Vibrant district on the San Francisco bay; headquarters by UCSF and the Gladstone Institutes

Catalyst Program Award Winner

UCSF’s translational accelerator focused on advancing UCSF discoveries with clinical impact and commercial potential

1st Place Award UCSF Innovation Ventures

Awarded by UCSF’s Entrepreneurship Center, a premier life science resource for faculty spinouts

Innovators and Risk Takers

United in our bold idea to create the world’s first universal AAV gene therapy